Stratum granulosum Totally Explained

Everything about Stratum Granulosum totally explained

In microscopic views of skin, the stratum granulosum layer of the epidermis lies between the stratum spinosum, below, and the stratum lucidum, above, in stratified squamous keratinized thick skin of palms and soles. Thin skin, which covers the rest of the body, lacks a definite stratum lucidum and stratum granulosum.
   The stratum granulosum layer typically contains 1 to 3 rows of squamous cells with many small basophilic granules in their cytoplasm.
   These prominent keratohyalin granules are not membrane-bound. Keratin bundles pass through the granules, which contain a phosphorylated histidine-rich protein and other cystine-rich proteins. The cells in the stratum granulosum contain also large amounts of filaggrin, a protein thought to serve in bundling keratin. Membrane-coated lamellar granules (0.1 to 0.3 micrometers) are also present and contain lipids. The lamellar granules are exocytosed in this layer to generate a waterproof barrier. This waterproofing also prevents life-sustaining nutrient transport, and thus leads to the characteristic cell death of the outer layers of keratinized epithelium.
   This is the highest layer in the epidermis where living cells are found; the stratum lucidum above appears clear due to auto-digestion of cellular organelles.
   This layer also includes lamellar granules and tonofibrils.

Further Information

Get more info on 'Stratum Granulosum'.

External Link Exchanges

Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:

<a href="http://stratum_granulosum.totallyexplained.com">Stratum granulosum Totally Explained</a>

Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned.